

Dr. Mario/Puzzle League features two of Nintendo's iconic puzzle games. While Dr. Mario was previously released on the GBA as part of the Classic NES Series, the version in this dual-pack has been specially enhanced for the Game Boy Advance hardware, rather than being a direct emulation of the original NES game. Puzzle League first appeared as Tetris Attack and was later rebranded as Pokémon Puzzle Challenge on the Game Boy Color several years ago. The GBA version has also been upgraded to take advantage of the system’s more advanced graphics capabilities and was previously available as an unlockable title through the GameCube–Game Boy Advance Link Cable in Nintendo Puzzle Collection for the GameCube.
| GBA | September 13, 2005 |


| Audio | Subtitles | Interface | |
|---|---|---|---|
| English (US) | ✓ | ||
| 日本語 | ✓ |