

After a devastating war that ravages most of the planet, Tuff E Nuff brings together four of Earth's toughest warriors to face off in brutal combat, earning the chance to challenge the powerful ruler. The game follows a classic beat 'em up format, incorporating all the usual genre staples. Each character has a unique set of punches, kicks, and throws, and they fight from their own home base. A 90-second timer can be enabled or disabled. Matches are best-of-three rounds, with points given for landed hits and for winning the match.
| SFAM | March 26, 1993 |
| SNES | December 31, 1993 |